Semaphorin 3A Signaling Through Neuropilin-1 Is an Early Trigger for Distal Axonopathy in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a motor neuron disease characterized by progressive distal axonopathy that precedes actual motor neuron death. Triggers for neuromuscular junction degeneration remain to be determined, but the axon repulsion factor semaphorin 3A (Sema3A), which is derived from...

Descripción completa

Detalles Bibliográficos
Autores principales: Venkova, Kalina, Christov, Alexander, Kamaluddin, Zarine, Kobalka, Peter, Siddiqui, Saaid, Hensley, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neuropathologists 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072440/
https://www.ncbi.nlm.nih.gov/pubmed/24918638
http://dx.doi.org/10.1097/NEN.0000000000000086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072440/
https://www.ncbi.nlm.nih.gov/pubmed/24918638
http://dx.doi.org/10.1097/NEN.0000000000000086

Ejemplares similares