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Immunostaining of Oxidized DJ-1 in Human and Mouse Brains

DJ-1, the product of a causative gene of a familial form of Parkinson disease, undergoes preferential oxidation of Cys106 (cysteine residue at position 106) under oxidative stress. Using specific monoclonal antibodies against Cys106 oxidized DJ-1 (oxDJ-1), we examined oxDJ-1 immunoreactivity in brai...

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Detalles Bibliográficos
Autores principales: Saito, Yoshiro, Miyasaka, Tomohiro, Hatsuta, Hiroyuki, Takahashi-Niki, Kazuko, Hayashi, Kojiro, Mita, Yuichiro, Kusano-Arai, Osamu, Iwanari, Hiroko, Ariga, Hiroyoshi, Hamakubo, Takao, Yoshida, Yasukazu, Niki, Etsuo, Murayama, Shigeo, Ihara, Yasuo, Noguchi, Noriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neuropathologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072441/
https://www.ncbi.nlm.nih.gov/pubmed/24918637
http://dx.doi.org/10.1097/NEN.0000000000000087