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Integrating Diverse Datasets Improves Developmental Enhancer Prediction

Gene-regulatory enhancers have been identified using various approaches, including evolutionary conservation, regulatory protein binding, chromatin modifications, and DNA sequence motifs. To integrate these different approaches, we developed EnhancerFinder, a two-step method for distinguishing devel...

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Detalles Bibliográficos
Autores principales: Erwin, Genevieve D., Oksenberg, Nir, Truty, Rebecca M., Kostka, Dennis, Murphy, Karl K., Ahituv, Nadav, Pollard, Katherine S., Capra, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072507/
https://www.ncbi.nlm.nih.gov/pubmed/24967590
http://dx.doi.org/10.1371/journal.pcbi.1003677