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Accurate, Model-Based Tuning of Synthetic Gene Expression Using Introns in S. cerevisiae

Introns are key regulators of eukaryotic gene expression and present a potentially powerful tool for the design of synthetic eukaryotic gene expression systems. However, intronic control over gene expression is governed by a multitude of complex, incompletely understood, regulatory mechanisms. Despi...

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Detalles Bibliográficos
Autores principales: Yofe, Ido, Zafrir, Zohar, Blau, Rachel, Schuldiner, Maya, Tuller, Tamir, Shapiro, Ehud, Ben-Yehezkel, Tuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072511/
https://www.ncbi.nlm.nih.gov/pubmed/24968317
http://dx.doi.org/10.1371/journal.pgen.1004407