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Accurate, Model-Based Tuning of Synthetic Gene Expression Using Introns in S. cerevisiae
Introns are key regulators of eukaryotic gene expression and present a potentially powerful tool for the design of synthetic eukaryotic gene expression systems. However, intronic control over gene expression is governed by a multitude of complex, incompletely understood, regulatory mechanisms. Despi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072511/ https://www.ncbi.nlm.nih.gov/pubmed/24968317 http://dx.doi.org/10.1371/journal.pgen.1004407 |