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Regulation of Gene Expression in Autoimmune Disease Loci and the Genetic Basis of Proliferation in CD4(+) Effector Memory T Cells

Genome-wide association studies (GWAS) and subsequent dense-genotyping of associated loci identified over a hundred single-nucleotide polymorphism (SNP) variants associated with the risk of rheumatoid arthritis (RA), type 1 diabetes (T1D), and celiac disease (CeD). Immunological and genetic studies...

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Detalles Bibliográficos
Autores principales: Hu, Xinli, Kim, Hyun, Raj, Towfique, Brennan, Patrick J., Trynka, Gosia, Teslovich, Nikola, Slowikowski, Kamil, Chen, Wei-Min, Onengut, Suna, Baecher-Allan, Clare, De Jager, Philip L., Rich, Stephen S., Stranger, Barbara E., Brenner, Michael B., Raychaudhuri, Soumya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072514/
https://www.ncbi.nlm.nih.gov/pubmed/24968232
http://dx.doi.org/10.1371/journal.pgen.1004404