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Hecate/Grip2a Acts to Reorganize the Cytoskeleton in the Symmetry-Breaking Event of Embryonic Axis Induction

Maternal homozygosity for three independent mutant hecate alleles results in embryos with reduced expression of dorsal organizer genes and defects in the formation of dorsoanterior structures. A positional cloning approach identified all hecate mutations as stop codons affecting the same gene, revea...

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Detalles Bibliográficos
Autores principales: Ge, Xiaoyan, Grotjahn, Danielle, Welch, Elaine, Lyman-Gingerich, Jamie, Holguin, Christiana, Dimitrova, Eva, Abrams, Elliot W., Gupta, Tripti, Marlow, Florence L., Yabe, Taijiro, Adler, Anna, Mullins, Mary C., Pelegri, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072529/
https://www.ncbi.nlm.nih.gov/pubmed/24967891
http://dx.doi.org/10.1371/journal.pgen.1004422