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Interplay between Chaperones and Protein Disorder Promotes the Evolution of Protein Networks
Evolution is driven by mutations, which lead to new protein functions but come at a cost to protein stability. Non-conservative substitutions are of interest in this regard because they may most profoundly affect both function and stability. Accordingly, organisms must balance the benefit of accepti...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072544/ https://www.ncbi.nlm.nih.gov/pubmed/24968255 http://dx.doi.org/10.1371/journal.pcbi.1003674 |