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Kinetochore genes are coordinately up-regulated in human tumors as part of a FoxM1-related cell division program

The key player in directing proper chromosome segregation is the macromolecular kinetochore complex, which mediates DNA–microtubule interactions. Previous studies testing individual kinetochore genes documented examples of their overexpression in tumors relative to normal tissue, leading to proposal...

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Detalles Bibliográficos
Autores principales: Thiru, Prathapan, Kern, David M., McKinley, Kara L., Monda, Julie K., Rago, Florencia, Su, Kuan-Chung, Tsinman, Tonia, Yarar, Defne, Bell, George W., Cheeseman, Iain M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072572/
https://www.ncbi.nlm.nih.gov/pubmed/24829384
http://dx.doi.org/10.1091/mbc.E14-03-0837