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Kinetochore genes are coordinately up-regulated in human tumors as part of a FoxM1-related cell division program
The key player in directing proper chromosome segregation is the macromolecular kinetochore complex, which mediates DNA–microtubule interactions. Previous studies testing individual kinetochore genes documented examples of their overexpression in tumors relative to normal tissue, leading to proposal...
Autores principales: | Thiru, Prathapan, Kern, David M., McKinley, Kara L., Monda, Julie K., Rago, Florencia, Su, Kuan-Chung, Tsinman, Tonia, Yarar, Defne, Bell, George W., Cheeseman, Iain M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072572/ https://www.ncbi.nlm.nih.gov/pubmed/24829384 http://dx.doi.org/10.1091/mbc.E14-03-0837 |
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