Cargando…

The lysosomal cathepsin protease CPL-1 plays a leading role in phagosomal degradation of apoptotic cells in Caenorhabditis elegans

During programmed cell death, the clearance of apoptotic cells is achieved by their phagocytosis and delivery to lysosomes for destruction in engulfing cells. However, the role of lysosomal proteases in cell corpse destruction is not understood. Here we report the identification of the lysosomal cat...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Meng, Liu, Yubing, Zhao, Liyuan, Gan, Qiwen, Wang, Xiaochen, Yang, Chonglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072580/
https://www.ncbi.nlm.nih.gov/pubmed/24829385
http://dx.doi.org/10.1091/mbc.E14-01-0015