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The lysosomal cathepsin protease CPL-1 plays a leading role in phagosomal degradation of apoptotic cells in Caenorhabditis elegans
During programmed cell death, the clearance of apoptotic cells is achieved by their phagocytosis and delivery to lysosomes for destruction in engulfing cells. However, the role of lysosomal proteases in cell corpse destruction is not understood. Here we report the identification of the lysosomal cat...
Autores principales: | Xu, Meng, Liu, Yubing, Zhao, Liyuan, Gan, Qiwen, Wang, Xiaochen, Yang, Chonglin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072580/ https://www.ncbi.nlm.nih.gov/pubmed/24829385 http://dx.doi.org/10.1091/mbc.E14-01-0015 |
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