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Drosha protein levels are translationally regulated during Xenopus oocyte maturation

MicroRNAs (miRNAs) are ∼21-nucleotide-long, single-stranded noncoding RNAs that regulate gene expression. Biogenesis of miRNAs is mediated by the two RNase III-like enzymes, Drosha and Dicer. Here we study miRNA biogenesis during maturation of Xenopus oocytes to eggs using microinjection of pri-miRN...

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Detalles Bibliográficos
Autores principales: Muggenhumer, Dominik, Vesely, Cornelia, Nimpf, Simon, Tian, Nan, Yongfeng, Jin, Jantsch, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072582/
https://www.ncbi.nlm.nih.gov/pubmed/24829383
http://dx.doi.org/10.1091/mbc.E13-07-0386