FGFR2 Is Amplified in the NCI-H716 Colorectal Cancer Cell Line and Is Required for Growth and Survival

Aberrant kinase activation resulting from mutation, amplification, or translocation can drive growth and survival in a subset of human cancer. FGFR2 is amplified in breast and gastric cancer, and we report here the first characterization of FGFR2 gene amplification in colorectal cancer in the NCI-H7...

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Detalles Bibliográficos
Autores principales: Mathur, Anjili, Ware, Christopher, Davis, Lenora, Gazdar, Adi, Pan, Bo-Sheng, Lutterbach, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072591/
https://www.ncbi.nlm.nih.gov/pubmed/24968263
http://dx.doi.org/10.1371/journal.pone.0098515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072591/
https://www.ncbi.nlm.nih.gov/pubmed/24968263
http://dx.doi.org/10.1371/journal.pone.0098515

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