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Concomitant Exposure to Ovalbumin and Endotoxin Augments Airway Inflammation but Not Airway Hyperresponsiveness in a Murine Model of Asthma

Varying concentrations of lipopolysaccharide (LPS) in ovalbumin (OVA) may influence the airway response to allergic sensitization and challenge. We assessed the contribution of LPS to allergic airway inflammatory responses following challenge with LPS-rich and LPS-free commercial OVA. BALB/c mice we...

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Detalles Bibliográficos
Autores principales: Mac Sharry, John, Shalaby, Karim H., Marchica, Cinzia, Farahnak, Soroor, Chieh-Li, Tien, Lapthorne, Susan, Qureshi, Salman T., Shanahan, Fergus, Martin, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072597/
https://www.ncbi.nlm.nih.gov/pubmed/24968337
http://dx.doi.org/10.1371/journal.pone.0098648