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Concomitant Exposure to Ovalbumin and Endotoxin Augments Airway Inflammation but Not Airway Hyperresponsiveness in a Murine Model of Asthma
Varying concentrations of lipopolysaccharide (LPS) in ovalbumin (OVA) may influence the airway response to allergic sensitization and challenge. We assessed the contribution of LPS to allergic airway inflammatory responses following challenge with LPS-rich and LPS-free commercial OVA. BALB/c mice we...
Autores principales: | Mac Sharry, John, Shalaby, Karim H., Marchica, Cinzia, Farahnak, Soroor, Chieh-Li, Tien, Lapthorne, Susan, Qureshi, Salman T., Shanahan, Fergus, Martin, James G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072597/ https://www.ncbi.nlm.nih.gov/pubmed/24968337 http://dx.doi.org/10.1371/journal.pone.0098648 |
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