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Combination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of Bim

BACKGROUND: A common approach to cancer therapy in clinical practice is the combination of several drugs to boost the anticancer activity of available drugs while suppressing their unwanted side effects. In this regard, we examined the efficacy of combination treatment with the widely-used genotoxic...

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Detalles Bibliográficos
Autores principales: Park, Hye-Kyung, Lee, Ji-Eun, Lim, Jaehwa, Jo, Da-Eun, Park, Soo-Ah, Suh, Pann-Ghill, Kang, Byoung Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072609/
https://www.ncbi.nlm.nih.gov/pubmed/24927938
http://dx.doi.org/10.1186/1471-2407-14-431