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Glycerol-3-Phosphate Acyltranferase-2 Behaves as a Cancer Testis Gene and Promotes Growth and Tumorigenicity of the Breast Cancer MDA-MB-231 Cell Line

The de novo synthesis of glycerolipids in mammalian cells begins with the acylation of glycerol-3-phosphate, catalyzed by glycerol-3-phosphate acyltransferase (GPAT). GPAT2 is a mitochondrial isoform primarily expressed in testis under physiological conditions. Because it is aberrantly expressed in...

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Detalles Bibliográficos
Autores principales: Pellon-Maison, Magali, Montanaro, Mauro A., Lacunza, Ezequiel, Garcia-Fabiani, Maria B., Soler-Gerino, Mercedes C., Cattaneo, Elizabeth R., Quiroga, Ivana Y., Abba, Martin C., Coleman, Rosalind A., Gonzalez-Baro, Maria R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072688/
https://www.ncbi.nlm.nih.gov/pubmed/24967918
http://dx.doi.org/10.1371/journal.pone.0100896