Cargando…

Glycerol-3-Phosphate Acyltranferase-2 Behaves as a Cancer Testis Gene and Promotes Growth and Tumorigenicity of the Breast Cancer MDA-MB-231 Cell Line

The de novo synthesis of glycerolipids in mammalian cells begins with the acylation of glycerol-3-phosphate, catalyzed by glycerol-3-phosphate acyltransferase (GPAT). GPAT2 is a mitochondrial isoform primarily expressed in testis under physiological conditions. Because it is aberrantly expressed in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pellon-Maison, Magali, Montanaro, Mauro A., Lacunza, Ezequiel, Garcia-Fabiani, Maria B., Soler-Gerino, Mercedes C., Cattaneo, Elizabeth R., Quiroga, Ivana Y., Abba, Martin C., Coleman, Rosalind A., Gonzalez-Baro, Maria R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072688/ https://www.ncbi.nlm.nih.gov/pubmed/24967918 http://dx.doi.org/10.1371/journal.pone.0100896

Ejemplares similares

Small non-coding RNA landscape is modified by GPAT2 silencing in MDA-MB-231 cells
por: Lacunza, Ezequiel, et al.
Publicado: (2018)

Glycerol-3-Phosphate Acyltransferase-2 Is Expressed in Spermatic Germ Cells and Incorporates Arachidonic Acid into Triacylglycerols
por: Cattaneo, Elizabeth R., et al.
Publicado: (2012)

Methylation of the Gpat2 promoter regulates transient expression during mouse spermatogenesis
por: Garcia-Fabiani, Maria B., et al.
Publicado: (2015)

Potential Effects of Chrysin on MDA-MB-231 Cells
por: Hong, Teh Ban, et al.
Publicado: (2010)

Loquat (Eriobotrya japonica) leaf extract inhibits the growth of MDA-MB-231 tumors in nude mouse xenografts and invasion of MDA-MB-231 cells
por: You, Mi-Kyoung, et al.
Publicado: (2016)

Citral induced apoptosis in MDA-MB-231 spheroid cells
por: Nigjeh, Siyamak Ebrahimi, et al.
Publicado: (2018)

Shock wave impact on the viability of MDA-MB-231 cells
por: Liao, Yingqian, et al.
Publicado: (2020)

Effects of FSTL1 on cell proliferation in breast cancer cell line MDA-MB-231 and its brain metastatic variant MDA-MB-231-BR
por: An, Jiaqiang, et al.
Publicado: (2017)

Temporin-GHb of Hylarana guentheri induces apoptosis by the mitochondrial pathway in MDA-MB-231 cells : Temporin-GHb induces MDA-MB-231 cell apoptosis
por: Liu, Yujun, et al.
Publicado: (2022)

Action and Signaling of Lysophosphatidylethanolamine in MDA-MB-231 Breast Cancer Cells
por: Park, Soo-Jin, et al.
Publicado: (2014)

Hypoxia regulates stemness of breast cancer MDA-MB-231 cells
por: Xie, Jing, et al.
Publicado: (2016)

Berberine Inhibits MDA-MB-231 Cells by Attenuating Their Inflammatory Responses
por: Zhao, Lina, et al.
Publicado: (2020)

Dehydrocorydaline inhibits the tumorigenesis of breast cancer MDA-MB-231 cells
por: Huang, Ying, et al.
Publicado: (2020)

Effects of osteopontin inhibition on radiosensitivity of MDA-MB-231 breast cancer cells
por: Hahnel, Antje, et al.
Publicado: (2010)

Anti-Cancer Effect of IN-2001 in MDA-MB-231 Human Breast Cancer
por: Min, Kyung Nan, et al.
Publicado: (2012)

STAT3 Knockdown Induces Tumor Formation by MDA-MB-231 Cells
por: Banerjee, Kasturi, et al.
Publicado: (2018)

Synergistic action of cisplatin and echistatin in MDA-MB-231 breast cancer cells
por: Czarnomysy, Robert, et al.
Publicado: (2016)

Proteomics Profiling of KAIMRC1 in Comparison to MDA-MB231 and MCF-7
por: Alghanem, Bandar, et al.
Publicado: (2020)

Effects of curcumin complexes on MDA-MB-231 breast cancer cell proliferation
por: Mohammed, Fatima, et al.
Publicado: (2020)

PRIMA-1(MET) Does Not Restore Vitamin D Sensitivity to MDA-MB-231 and MDA-MB-468 Triple-Negative Breast Cancer Cells
por: Kotob, Shadi N., et al.
Publicado: (2023)

Development of Resistance towards Artesunate in MDA-MB-231 Human Breast Cancer Cells
por: Bachmeier, Beatrice, et al.
Publicado: (2011)

Polyphenols Sensitization Potentiates Susceptibility of MCF-7 and MDA MB-231 Cells to Centchroman
por: Singh, Neetu, et al.
Publicado: (2012)

Phenotypic Switch Induced by Simulated Microgravity on MDA-MB-231 Breast Cancer Cells
por: Masiello, Maria Grazia, et al.
Publicado: (2014)

Effects of Lovastatin on MDA-MB-231 Breast Cancer Cells: An Antibody Microarray Analysis
por: Yang, Tao, et al.
Publicado: (2016)

Optimized Method for Untargeted Metabolomics Analysis of MDA-MB-231 Breast Cancer Cells
por: Peterson, Amanda L., et al.
Publicado: (2016)

Antitumor effects of Xi Huang pills on MDA-MB-231 cells in vitro and in vivo
por: Zheng, Wenxian, et al.
Publicado: (2018)

Elastin molecular aging promotes MDA‐MB‐231 breast cancer cell invasiveness
por: Salesse, Stéphanie, et al.
Publicado: (2018)

Allyl Isothiocyanate Exhibits No Anticancer Activity in MDA-MB-231 Breast Cancer Cells
por: Sayeed, Md. Abu, et al.
Publicado: (2018)

Ginseng polysaccharide inhibits MDA-MB-231 cell proliferation by activating the inflammatory response
por: Zhou, Haoliang, et al.
Publicado: (2020)

Characterization of Triple-Negative Breast Cancer MDA-MB-231 Cell Spheroid Model
por: Huang, Zhaoming, et al.
Publicado: (2020)

Mannoside-Modified Branched Gold Nanoparticles for Photothermal Therapy to MDA-MB-231 Cells
por: Lin, Han-Chen, et al.
Publicado: (2020)

Arctigenin Enhances the Cytotoxic Effect of Doxorubicin in MDA-MB-231 Breast Cancer Cells
por: Lee, Kyu-Shik, et al.
Publicado: (2020)

Amikacin Suppresses Human Breast Cancer Cell MDA-MB-231 Migration and Invasion
por: Wang, Yun-Hsin, et al.
Publicado: (2020)

Flavokawain B induced cytotoxicity in two breast cancer cell lines, MCF-7 and MDA-MB231 and inhibited the metastatic potential of MDA-MB231 via the regulation of several tyrosine kinases In vitro
por: Abu, Nadiah, et al.
Publicado: (2016)

Microcell-mediated transfer of chromosome 6 into the breast cancer cell line MDA-MB-231: a specific set of genes is involved in the reversion of the tumorigenic phenotype
por: Strissel, J, et al.
Publicado: (2005)

Antibacterial Synthetic Peptides Derived from Bovine Lactoferricin Exhibit Cytotoxic Effect against MDA-MB-468 and MDA-MB-231 Breast Cancer Cell Lines
por: Vargas Casanova, Yerly, et al.
Publicado: (2017)

1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol ameliorates EGF-induced MMP-9 expression by promoting receptor desensitization in MDA-MB-231 cells
por: Yang, Kwang Hoon, et al.
Publicado: (2020)

Retroviral-infection increases tumorigenic potential of MDA-MB-231 breast carcinoma cells by expanding an aldehyde dehydrogenase (ALDH1) positive stem-cell like population
por: Wegman-Points, Lauren J., et al.
Publicado: (2014)

A highly invasive subpopulation of MDA-MB-231 breast cancer cells shows accelerated growth, differential chemoresistance, features of apocrine tumors and reduced tumorigenicity in vivo
por: Amaro, Adriana, et al.
Publicado: (2016)

Relaxin reduces xenograft tumour growth of human MDA-MB-231 breast cancer cells
por: Radestock, Yvonne, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_c4ju3turj145hem86gejdi8uhq