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Glycerol-3-Phosphate Acyltranferase-2 Behaves as a Cancer Testis Gene and Promotes Growth and Tumorigenicity of the Breast Cancer MDA-MB-231 Cell Line
The de novo synthesis of glycerolipids in mammalian cells begins with the acylation of glycerol-3-phosphate, catalyzed by glycerol-3-phosphate acyltransferase (GPAT). GPAT2 is a mitochondrial isoform primarily expressed in testis under physiological conditions. Because it is aberrantly expressed in...
Autores principales: | Pellon-Maison, Magali, Montanaro, Mauro A., Lacunza, Ezequiel, Garcia-Fabiani, Maria B., Soler-Gerino, Mercedes C., Cattaneo, Elizabeth R., Quiroga, Ivana Y., Abba, Martin C., Coleman, Rosalind A., Gonzalez-Baro, Maria R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072688/ https://www.ncbi.nlm.nih.gov/pubmed/24967918 http://dx.doi.org/10.1371/journal.pone.0100896 |
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