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RNA Stimulates Aurora B Kinase Activity during Mitosis

Accurate chromosome segregation is essential for cell viability. The mitotic spindle is crucial for chromosome segregation, but much remains unknown about factors that regulate spindle assembly. Recent work implicates RNA in promoting proper spindle assembly independently of mRNA translation; howeve...

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Detalles Bibliográficos
Autores principales: Jambhekar, Ashwini, Emerman, Amy B., Schweidenback, Caterina T. H., Blower, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072698/
https://www.ncbi.nlm.nih.gov/pubmed/24968351
http://dx.doi.org/10.1371/journal.pone.0100748