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Role of Endogenous GLP-1 and GIP in Beta Cell Compensatory Responses to Insulin Resistance and Cellular Stress

Role of GLP-1 and GIP in beta cell compensatory responses to beta cell attack and insulin resistance were examined in C57BL/6 mice lacking functional receptors for GLP-1 and GIP. Mice were treated with multiple low dose streptozotocin or hydrocortisone. Islet parameters were assessed by immunohistoc...

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Detalles Bibliográficos
Autores principales: Vasu, Srividya, Moffett, R. Charlotte, Thorens, Bernard, Flatt, Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072716/
https://www.ncbi.nlm.nih.gov/pubmed/24967820
http://dx.doi.org/10.1371/journal.pone.0101005