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Rab11 Regulates Trafficking of Trans-sialidase to the Plasma Membrane through the Contractile Vacuole Complex of Trypanosoma cruzi

Trypanosoma cruzi is the etiologic agent of Chagas disease. Although this is not a free-living organism it has conserved a contractile vacuole complex (CVC) to regulate its osmolarity. This obligate intracellular pathogen is, in addition, dependent on surface proteins to invade its hosts. Here we us...

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Detalles Bibliográficos
Autores principales: Niyogi, Sayantanee, Mucci, Juan, Campetella, Oscar, Docampo, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072791/
https://www.ncbi.nlm.nih.gov/pubmed/24968013
http://dx.doi.org/10.1371/journal.ppat.1004224