Lentiviral and targeted cellular barcoding reveals ongoing clonal dynamics of cell lines in vitro and in vivo

BACKGROUND: Cell lines are often regarded as clonal, even though this simplifies what is known about mutagenesis, transformation and other processes that destabilize them over time. Monitoring these clonal dynamics is important for multiple areas of biomedical research, including stem cell and cance...

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Detalles Bibliográficos
Autores principales: Porter, Shaina N, Baker, Lee C, Mittelman, David, Porteus, Matthew H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073073/
https://www.ncbi.nlm.nih.gov/pubmed/24886633
http://dx.doi.org/10.1186/gb-2014-15-5-r75

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073073/
https://www.ncbi.nlm.nih.gov/pubmed/24886633
http://dx.doi.org/10.1186/gb-2014-15-5-r75

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