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Differential Effects of Indoxyl Sulfate and Inorganic Phosphate in a Murine Cerebral Endothelial Cell Line (bEnd.3)

Endothelial dysfunction plays a key role in stroke in chronic kidney disease patients. To explore the underlying mechanisms, we evaluated the effects of two uremic toxins on cerebral endothelium function. bEnd.3 cells were exposed to indoxyl sulfate (IS) and inorganic phosphate (Pi). Nitric oxide (N...

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Detalles Bibliográficos
Autores principales: Stinghen, Andréa E. M., Chillon, Jean-Marc, Massy, Ziad A., Boullier, Agnès
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073127/
https://www.ncbi.nlm.nih.gov/pubmed/24902077
http://dx.doi.org/10.3390/toxins6061742