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Hooking the big one: the potential of zebrafish xenotransplantation to reform cancer drug screening in the genomic era

The current preclinical pipeline for drug discovery can be cumbersome and costly, which limits the number of compounds that can effectively be transitioned to use as therapies. Chemical screens in zebrafish have uncovered new uses for existing drugs and identified promising new compounds from large...

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Detalles Bibliográficos
Autores principales: Veinotte, Chansey J., Dellaire, Graham, Berman, Jason N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073264/
https://www.ncbi.nlm.nih.gov/pubmed/24973744
http://dx.doi.org/10.1242/dmm.015784