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Molecularly defined unfolded protein response subclasses have distinct correlations with fatty liver disease in zebrafish

The unfolded protein response (UPR) is a complex network of sensors and target genes that ensure efficient folding of secretory proteins in the endoplasmic reticulum (ER). UPR activation is mediated by three main sensors, which regulate the expression of hundreds of targets. UPR activation can resul...

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Detalles Bibliográficos
Autores principales: Vacaru, Ana M., Di Narzo, Antonio Fabio, Howarth, Deanna L., Tsedensodnom, Orkhontuya, Imrie, Dru, Cinaroglu, Ayca, Amin, Salma, Hao, Ke, Sadler, Kirsten C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073272/
https://www.ncbi.nlm.nih.gov/pubmed/24973751
http://dx.doi.org/10.1242/dmm.014472