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Molecularly defined unfolded protein response subclasses have distinct correlations with fatty liver disease in zebrafish
The unfolded protein response (UPR) is a complex network of sensors and target genes that ensure efficient folding of secretory proteins in the endoplasmic reticulum (ER). UPR activation is mediated by three main sensors, which regulate the expression of hundreds of targets. UPR activation can resul...
Autores principales: | Vacaru, Ana M., Di Narzo, Antonio Fabio, Howarth, Deanna L., Tsedensodnom, Orkhontuya, Imrie, Dru, Cinaroglu, Ayca, Amin, Salma, Hao, Ke, Sadler, Kirsten C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073272/ https://www.ncbi.nlm.nih.gov/pubmed/24973751 http://dx.doi.org/10.1242/dmm.014472 |
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