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Zebrafish reporter lines reveal in vivo signaling pathway activities involved in pancreatic cancer

Pancreatic adenocarcinoma, one of the worst malignancies of the exocrine pancreas, is a solid tumor with increasing incidence and mortality in industrialized countries. This condition is usually driven by oncogenic KRAS point mutations and evolves into a highly aggressive metastatic carcinoma due to...

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Detalles Bibliográficos
Autores principales: Schiavone, Marco, Rampazzo, Elena, Casari, Alessandro, Battilana, Giusy, Persano, Luca, Moro, Enrico, Liu, Shu, Leach, Steve D., Tiso, Natascia, Argenton, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073277/
https://www.ncbi.nlm.nih.gov/pubmed/24878567
http://dx.doi.org/10.1242/dmm.014969