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A zebrafish model of chordoma initiated by notochord-driven expression of HRASV12

Chordoma is a malignant tumor thought to arise from remnants of the embryonic notochord, with its origin in the bones of the axial skeleton. Surgical resection is the standard treatment, usually in combination with radiation therapy, but neither chemotherapeutic nor targeted therapeutic approaches h...

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Detalles Bibliográficos
Autores principales: Burger, Alexa, Vasilyev, Aleksandr, Tomar, Ritu, Selig, Martin K., Nielsen, G. Petur, Peterson, Randall T., Drummond, Iain A., Haber, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073279/
https://www.ncbi.nlm.nih.gov/pubmed/24311731
http://dx.doi.org/10.1242/dmm.013128