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A zebrafish model of chordoma initiated by notochord-driven expression of HRASV12
Chordoma is a malignant tumor thought to arise from remnants of the embryonic notochord, with its origin in the bones of the axial skeleton. Surgical resection is the standard treatment, usually in combination with radiation therapy, but neither chemotherapeutic nor targeted therapeutic approaches h...
Autores principales: | Burger, Alexa, Vasilyev, Aleksandr, Tomar, Ritu, Selig, Martin K., Nielsen, G. Petur, Peterson, Randall T., Drummond, Iain A., Haber, Daniel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073279/ https://www.ncbi.nlm.nih.gov/pubmed/24311731 http://dx.doi.org/10.1242/dmm.013128 |
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