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Structure of cellular ESCRT-III spirals and their relationship to HIV budding

The ESCRT machinery along with the AAA+ ATPase Vps4 drive membrane scission for trafficking into multivesicular bodies in the endocytic pathway and for the topologically related processes of viral budding and cytokinesis, but how they accomplish this remains unclear. Using deep-etch electron microsc...

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Detalles Bibliográficos
Autores principales: Cashikar, Anil G, Shim, Soomin, Roth, Robyn, Maldazys, Michael R, Heuser, John E, Hanson, Phyllis I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073282/
https://www.ncbi.nlm.nih.gov/pubmed/24878737
http://dx.doi.org/10.7554/eLife.02184