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Enhanced stability of hippocampal place representation caused by reduced magnesium block of NMDA receptors in the dentate gyrus

BACKGROUND: Voltage-dependent block of the NMDA receptor by Mg(2+) is thought to be central to the unique involvement of this receptor in higher brain functions. However, the in vivo role of the Mg(2+) block in the mammalian brain has not yet been investigated, because brain-wide loss of the Mg(2+)...

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Detalles Bibliográficos
Autores principales: Hayashi, Yuichiro, Nabeshima, Yoko, Kobayashi, Katsunori, Miyakawa, Tsuyoshi, Tanda, Koichi, Takao, Keizo, Suzuki, Hidenori, Esumi, Eisaku, Noguchi, Shigeru, Matsuda, Yukiko, Sasaoka, Toshikuni, Noda, Tetsuo, Miyazaki, Jun-ichi, Mishina, Masayoshi, Funabiki, Kazuo, Nabeshima, Yo-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073519/
https://www.ncbi.nlm.nih.gov/pubmed/24893573
http://dx.doi.org/10.1186/1756-6606-7-44