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Detecting overlapping protein complexes based on a generative model with functional and topological properties

BACKGROUND: Identification of protein complexes can help us get a better understanding of cellular mechanism. With the increasing availability of large-scale protein-protein interaction (PPI) data, numerous computational approaches have been proposed to detect complexes from the PPI networks. Howeve...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Fei, Dai, Dao-Qing, Ou-Yang, Le, Yan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073817/
https://www.ncbi.nlm.nih.gov/pubmed/24928559
http://dx.doi.org/10.1186/1471-2105-15-186