Twist1- and Twist2-Haploinsufficiency Results in Reduced Bone Formation

BACKGROUND: Twist1 and Twist2 are highly homologous bHLH transcription factors that exhibit extensive highly overlapping expression profiles during development. While both proteins have been shown to inhibit osteogenesis, only Twist1 haploinsufficiency is associated with the premature synostosis of...

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Detalles Bibliográficos
Autores principales: Huang, Yanyu, Meng, Tian, Wang, Suzhen, Zhang, Hua, Mues, Gabriele, Qin, Chunlin, Feng, Jian Q., D'Souza, Rena N., Lu, Yongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074031/
https://www.ncbi.nlm.nih.gov/pubmed/24971743
http://dx.doi.org/10.1371/journal.pone.0099331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074031/
https://www.ncbi.nlm.nih.gov/pubmed/24971743
http://dx.doi.org/10.1371/journal.pone.0099331

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