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Twist1- and Twist2-Haploinsufficiency Results in Reduced Bone Formation
BACKGROUND: Twist1 and Twist2 are highly homologous bHLH transcription factors that exhibit extensive highly overlapping expression profiles during development. While both proteins have been shown to inhibit osteogenesis, only Twist1 haploinsufficiency is associated with the premature synostosis of...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074031/ https://www.ncbi.nlm.nih.gov/pubmed/24971743 http://dx.doi.org/10.1371/journal.pone.0099331 |