Gefitinib and Luteolin Cause Growth Arrest of Human Prostate Cancer PC-3 Cells via Inhibition of Cyclin G-Associated Kinase and Induction of miR-630

Cyclin G-associated kinase (GAK), a key player in clathrin-mediated membrane trafficking, is overexpressed in various cancer cells. Here, we report that GAK expression is positively correlated with the Gleason score in surgical specimens from prostate cancer patients. Embryonic fibroblasts from knoc...

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Detalles Bibliográficos
Autores principales: Sakurai, Minami A., Ozaki, Yuki, Okuzaki, Daisuke, Naito, Yoko, Sasakura, Towa, Okamoto, Ayumi, Tabara, Hiroe, Inoue, Takao, Hagiyama, Man, Ito, Akihiko, Yabuta, Norikazu, Nojima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074034/
https://www.ncbi.nlm.nih.gov/pubmed/24971999
http://dx.doi.org/10.1371/journal.pone.0100124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074034/
https://www.ncbi.nlm.nih.gov/pubmed/24971999
http://dx.doi.org/10.1371/journal.pone.0100124

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