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Polymorphisms in the Inflammatory Pathway Genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG Are Associated with Susceptibility of Inflammatory Bowel Disease in a Danish Cohort

BACKGROUND: The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), result from the combined effects of susceptibility genes and environmental factors. Polymorphisms in genes regulating inflammation may explain part of the genetic heritage. METHODS: Using a cand...

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Detalles Bibliográficos
Autores principales: Bank, Steffen, Skytt Andersen, Paal, Burisch, Johan, Pedersen, Natalia, Roug, Stine, Galsgaard, Julie, Ydegaard Turino, Stine, Broder Brodersen, Jacob, Rashid, Shaista, Kaiser Rasmussen, Britt, Avlund, Sara, Bastholm Olesen, Thomas, Jürgen Hoffmann, Hans, Kragh Thomsen, Marianne, Østergaard Thomsen, Vibeke, Frydenberg, Morten, Andersen Nexø, Bjørn, Sode, Jacob, Vogel, Ulla, Andersen, Vibeke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074037/
https://www.ncbi.nlm.nih.gov/pubmed/24971461
http://dx.doi.org/10.1371/journal.pone.0098815