Cargando…

Polymorphisms in the Inflammatory Pathway Genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG Are Associated with Susceptibility of Inflammatory Bowel Disease in a Danish Cohort

BACKGROUND: The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), result from the combined effects of susceptibility genes and environmental factors. Polymorphisms in genes regulating inflammation may explain part of the genetic heritage. METHODS: Using a cand...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bank, Steffen, Skytt Andersen, Paal, Burisch, Johan, Pedersen, Natalia, Roug, Stine, Galsgaard, Julie, Ydegaard Turino, Stine, Broder Brodersen, Jacob, Rashid, Shaista, Kaiser Rasmussen, Britt, Avlund, Sara, Bastholm Olesen, Thomas, Jürgen Hoffmann, Hans, Kragh Thomsen, Marianne, Østergaard Thomsen, Vibeke, Frydenberg, Morten, Andersen Nexø, Bjørn, Sode, Jacob, Vogel, Ulla, Andersen, Vibeke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074037/ https://www.ncbi.nlm.nih.gov/pubmed/24971461 http://dx.doi.org/10.1371/journal.pone.0098815

Ejemplares similares

Polymorphisms in the Toll-Like Receptor and the IL-23/IL-17 Pathways Were Associated with Susceptibility to Inflammatory Bowel Disease in a Danish Cohort
por: Bank, Steffen, et al.
Publicado: (2015)

Genetically determined high activities of the TNF-alpha, IL23/IL17, and NFkB pathways were associated with increased risk of ankylosing spondylitis
por: Sode, Jacob, et al.
Publicado: (2018)

Microglia Induce Neurotoxic IL-17+ γδ T Cells Dependent on TLR2, TLR4, and TLR9 Activation
por: Derkow, Katja, et al.
Publicado: (2015)

The activation of CD14, TLR4, and TLR2 by mmLDL induces IL-1β, IL-6, and IL-10 secretion in human monocytes and macrophages
por: Chávez-Sánchez, Luis, et al.
Publicado: (2010)

Differential post-transcriptional regulation of IL-10 by TLR2 and TLR4-activated macrophages
por: Teixeira-Coelho, Maria, et al.
Publicado: (2014)

Targeting TLR/IL-1R Signalling in Human Diseases
por: Loiarro, Maria, et al.
Publicado: (2010)

IL-1-driven cartilage and bone destruction are dependent on Toll-like receptor (TLR) 4, but not TLR2
por: Abdollahi-Roodsaz, S, et al.
Publicado: (2005)

Genetic Diversity of IFγ, IL1β, TLR2, and TLR8 Loci in Pulmonary Tuberculosis in Kazakhstan
por: Yerezhepov, Dauren, et al.
Publicado: (2014)

Anti-TNF Treatment Response in Rheumatoid Arthritis Patients Is Associated with Genetic Variation in the NLRP3-Inflammasome
por: Sode, Jacob, et al.
Publicado: (2014)

Inhibitory effects of Ephedra alte on IL-6, hybrid TLR4, TNF-α, IL-1β, and extracted TLR4 receptors: in silico molecular docking
por: Salman, Haya Ayyal, et al.
Publicado: (2022)

TLR2 and endosomal TLR-mediated secretion of IL-10 and immune suppression in response to phagosome-confined Listeria monocytogenes
por: Nguyen, Brittney N., et al.
Publicado: (2020)

TLR9–IL-2 axis exacerbates allergic asthma by preventing IL-17A hyperproduction
por: Murakami, Yusuke, et al.
Publicado: (2020)

Pellino Proteins: Novel Players in TLR and IL-1R Signalling
por: Schauvliege, Reinout, et al.
Publicado: (2007)

TLR10 and NFKBIA contributed to the risk of hip osteoarthritis: systematic evaluation based on Han Chinese population
por: Tang, Hongtao, et al.
Publicado: (2018)

Reciprocal regulation of IL-23 and IL-12 following co-activation of Dectin-1 and TLR signaling pathways
por: Dennehy, Kevin M, et al.
Publicado: (2009)

TLR2 Regulates Mast Cell IL-6 and IL-13 Production During Listeria monocytogenes Infection
por: Soria-Castro, Rodolfo, et al.
Publicado: (2021)

Association between single nucleotide polymorphisms (SNPs) of IL1, IL12, IL28 and TLR4 and symptoms of congenital cytomegalovirus infection
por: Jedlińska-Pijanowska, Dominika, et al.
Publicado: (2020)

IL-33 protects mice from sepsis by inhibiting TLR4 signaling
por: Alves-Filho, JC, et al.
Publicado: (2009)

TLR2 was overexpressed independent of IL-6 in patients with valvular atrial fibrillation()
por: Wang, Jian, et al.
Publicado: (2011)

Sex Differences in the Response to Viral Infections: TLR8 and TLR9 Ligand Stimulation Induce Higher IL10 Production in Males
por: Torcia, Maria Gabriella, et al.
Publicado: (2012)

IL-4 Suppresses the Responses to TLR7 and TLR9 Stimulation and Increases the Permissiveness to Retroviral Infection of Murine Conventional Dendritic Cells
por: Sriram, Uma, et al.
Publicado: (2014)

Role of HMGB1/TLR4 and IL-1β/IL-1R1 Signaling Pathways in Epilepsy
por: Zhang, Shaohui, et al.
Publicado: (2022)

TNFA and IL10 Gene Polymorphisms are not Associated with Periodontitis in Brazilians
por: Moreira, P. R, et al.
Publicado: (2009)

Polymorphisms in NFKB1 and TLR4 and Interaction with Dietary and Life Style Factors in Relation to Colorectal Cancer in a Danish Prospective Case-Cohort Study
por: Kopp, Tine Iskov, et al.
Publicado: (2015)

TLR7 agonist induced repression of hepatocellular carcinoma via the TLR7-IKK-NF-κB-IL6 signaling pathway
por: REN, XINGBIN, et al.
Publicado: (2016)

Differential Expression of IFN-γ, IL-10, TLR1, and TLR2 and Their Potential Effects on Downgrading Leprosy Reaction and Erythema Nodosum Leprosum
por: Antunes, Douglas Eulálio, et al.
Publicado: (2019)

IL-6 Amplifies TLR Mediated Cytokine and Chemokine Production: Implications for the Pathogenesis of Rheumatic Inflammatory Diseases
por: Caiello, Ivan, et al.
Publicado: (2014)

Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages
por: Sarir, Hadi, et al.
Publicado: (2009)

TLR3 Agonist Poly-IC Induces IL-33 and Promotes Myelin Repair
por: Natarajan, Chandramohan, et al.
Publicado: (2016)

TLR2 Elicits IL-17-Mediated RANKL Expression, IL-17, and OPG Production in Neutrophils from Arthritic Mice
por: Milanova, Viktoriya, et al.
Publicado: (2014)

Morphine compromises bronchial epithelial TLR2/IL17R signaling crosstalk, necessary for lung IL17 homeostasis
por: Banerjee, Santanu, et al.
Publicado: (2015)

IL-4 and IL-13 regulate TLR expression and eosinophil-basophil differentiation of cord blood CD34(+) progenitor cells
por: Reece, Pia, et al.
Publicado: (2014)

Selective Inhibitors of Kv11.1 Regulate IL-6 Expression by Macrophages in Response to TLR/IL-1R Ligands
por: Hunter, Cheryl, et al.
Publicado: (2010)

Aberrant intestinal microbiota due to IL-1 receptor antagonist deficiency promotes IL-17- and TLR4-dependent arthritis
por: Rogier, Rebecca, et al.
Publicado: (2017)

Genetic Variations in Pattern Recognition Receptor Loci Are Associated with Anti-TNF Response in Patients with Rheumatoid Arthritis
por: Sode, Jacob, et al.
Publicado: (2015)

Induction of TLR-2 and TLR-5 Expression by Helicobacter pylori Switches cagPAI-Dependent Signalling Leading to the Secretion of IL-8 and TNF-α
por: Kumar Pachathundikandi, Suneesh, et al.
Publicado: (2011)

TLR3 and TLR7 Modulate IgE Production in Antigen Induced Pulmonary Inflammation via Influencing IL-4 Expression in Immune Organs
por: Meng, Liesu, et al.
Publicado: (2011)

IL-1R8 Downregulation and Concomitant TLR7 and TLR9 Upregulation Are Related to the Pathogenesis of Canine Diffuse Large B-Cell Lymphoma
por: Riva, Federica, et al.
Publicado: (2022)

Neutrophil-Mediated Lung Injury Both via TLR2-Dependent Production of IL-1α and IL-12 p40, and TLR2-Independent CARDS Toxin after Mycoplasma pneumoniae Infection in Mice
por: Tamiya, Shigeyuki, et al.
Publicado: (2021)

TLR2 Expression in Relation to IL-6 and IL-1β and their Natural Regulators Production by PMN and PBMC in Patients with Lyme Disease
por: Jablonska, Ewa, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_vj78ps0tl5o4kkfjqfgg4pag6r