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Alu and LINE-1 Hypomethylation Is Associated with HER2 Enriched Subtype of Breast Cancer

The changes in DNA methylation status in cancer cells are characterized by hypermethylation of promoter CpG islands and diffuse genomic hypomethylation. Alu and long interspersed nucleotide element-1 (LINE-1) are non-coding genomic repetitive sequences and methylation of these elements can be used a...

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Detalles Bibliográficos
Autores principales: Park, So Yeon, Seo, An Na, Jung, Hae Yoen, Gwak, Jae Moon, Jung, Namhee, Cho, Nam-Yun, Kang, Gyeong Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074093/
https://www.ncbi.nlm.nih.gov/pubmed/24971511
http://dx.doi.org/10.1371/journal.pone.0100429