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Alu and LINE-1 Hypomethylation Is Associated with HER2 Enriched Subtype of Breast Cancer
The changes in DNA methylation status in cancer cells are characterized by hypermethylation of promoter CpG islands and diffuse genomic hypomethylation. Alu and long interspersed nucleotide element-1 (LINE-1) are non-coding genomic repetitive sequences and methylation of these elements can be used a...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074093/ https://www.ncbi.nlm.nih.gov/pubmed/24971511 http://dx.doi.org/10.1371/journal.pone.0100429 |