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A Novel Function for Lysyl Oxidase in Pluripotent Mesenchymal Cell Proliferation and Relevance to Inflammation-Associated Osteopenia

Lysyl oxidase is a multifunctional enzyme required for collagen biosynthesis. Various growth factors regulate lysyl oxidase during osteoblast differentiation, subject to modulation by cytokines such as TNF-α in inflammatory osteopenic disorders including diabetic bone disease. Canonical Wnt signalin...

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Detalles Bibliográficos
Autores principales: Khosravi, Roozbeh, Sodek, Katharine L., Xu, Wan-Peng, Bais, Manish V., Saxena, Debashree, Faibish, Michael, Trackman, Philip C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074096/
https://www.ncbi.nlm.nih.gov/pubmed/24971753
http://dx.doi.org/10.1371/journal.pone.0100669