Cargando…

A Novel Function for Lysyl Oxidase in Pluripotent Mesenchymal Cell Proliferation and Relevance to Inflammation-Associated Osteopenia

Lysyl oxidase is a multifunctional enzyme required for collagen biosynthesis. Various growth factors regulate lysyl oxidase during osteoblast differentiation, subject to modulation by cytokines such as TNF-α in inflammatory osteopenic disorders including diabetic bone disease. Canonical Wnt signalin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khosravi, Roozbeh, Sodek, Katharine L., Xu, Wan-Peng, Bais, Manish V., Saxena, Debashree, Faibish, Michael, Trackman, Philip C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074096/ https://www.ncbi.nlm.nih.gov/pubmed/24971753 http://dx.doi.org/10.1371/journal.pone.0100669

Ejemplares similares

Multifunctional Lysyl Oxidases
por: Trackman, Philip C.
Publicado: (2023)

Effects of Tumor Suppressor Lysyl Oxidase Propeptide on Prostate Cancer Xenograft Growth and Its Direct Interactions with DNA Repair Pathways
por: Bais, Manish V., et al.
Publicado: (2014)

Recombinant Lysyl Oxidase Propeptide Protein Inhibits Growth and Promotes Apoptosis of Pre-Existing Murine Breast Cancer Xenografts
por: Bais, Manish V., et al.
Publicado: (2012)

β-Catenin mediates glucose-dependent insulinotropic polypeptide increases in lysyl oxidase expression in osteoblasts()
por: Daley, Eileen J., et al.
Publicado: (2021)

Functions and Mechanisms of Pro-Lysyl Oxidase Processing in Cancers and Eye Pathologies with a Focus on Diabetic Retinopathy
por: Trackman, Philip C., et al.
Publicado: (2022)

Downregulation of Lysyl Oxidase Protects Retinal Endothelial Cells From High Glucose–Induced Apoptosis
por: Kim, Dongjoon, et al.
Publicado: (2017)

Impaired Gastric Hormone Regulation of Osteoblasts and Lysyl Oxidase Drives Bone Disease in Diabetes Mellitus
por: Daley, Eileen J, et al.
Publicado: (2019)

The Interactome of Cancer-Related Lysyl Oxidase and Lysyl Oxidase-Like Proteins
por: Vallet, Sylvain D., et al.
Publicado: (2020)

Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-AB
por: Mahjour, Faranak, et al.
Publicado: (2019)

Lysyl Oxidase at the Crossroads of Mesenchymal Stem Cells and Epithelial-Mesenchymal Transition
por: Thomas, Clémence, et al.
Publicado: (2013)

Anabolic role of lysyl oxidase like-2 in cartilage of knee and temporomandibular joints with osteoarthritis
por: Alshenibr, Weam, et al.
Publicado: (2017)

High Glucose Increases Lysyl Oxidase Expression and Activity in Retinal Endothelial Cells: Mechanism for Compromised Extracellular Matrix Barrier Function
por: Chronopoulos, Argyrios, et al.
Publicado: (2010)

The Lysyl Oxidase G473A Polymorphism Exacerbates Oral Cancer Development in Humans and Mice
por: Peymanfar, Yaser, et al.
Publicado: (2023)

Clinical relevance of lysyl oxidase-like 2 and functional mechanisms in glioma
por: Du, Xiao-Guang, et al.
Publicado: (2018)

Origin and evolution of lysyl oxidases
por: Grau-Bové, Xavier, et al.
Publicado: (2015)

Lysyl Oxidase and the Tumor Microenvironment
por: Wang, Tong-Hong, et al.
Publicado: (2016)

Overhydroxylation of Lysine of Collagen Increases Uterine Fibroids Proliferation: Roles of Lysyl Hydroxylases, Lysyl Oxidases, and Matrix Metalloproteinases
por: Kamel, Marwa, et al.
Publicado: (2017)

Blimp1 Activation by AP-1 in Human Lung Cancer Cells Promotes a Migratory Phenotype and Is Inhibited by the Lysyl Oxidase Propeptide
por: Yu, Ziyang, et al.
Publicado: (2012)

Lysyl Oxidase-Like 2 Protects against Progressive and Aging Related Knee Joint Osteoarthritis in Mice
por: Tashkandi, Mustafa, et al.
Publicado: (2019)

Erratum to “Overhydroxylation of Lysine of Collagen Increases Uterine Fibroids Proliferation: Roles of Lysyl Hydroxylases, Lysyl Oxidases, and Matrix Metalloproteinases”
por: Kamel, Marwa, et al.
Publicado: (2018)

Lysyl Oxidase Pro-peptide Inhibits Prostate Cancer Cell Growth by Mechanisms that Target FGF-2-Cell Binding and Signaling
por: Palamakumbura, Amitha H., et al.
Publicado: (2009)

Inhibition of CIN85-Mediated Invasion by a Novel SH3 Domain Binding Motif in the Lysyl Oxidase Propeptide
por: Sato, Seiichi, et al.
Publicado: (2013)

Lysyl Oxidase Polymorphisms and Susceptibility to Osteosarcoma
por: Liu, Yang, et al.
Publicado: (2012)

An in situ activity assay for lysyl oxidases
por: Wang, Huilei, et al.
Publicado: (2021)

Serum Lysyl Oxidase Levels and Lysyl Oxidase Gene Polymorphism in Ovarian Cancer Patients of Eastern Indian Population
por: Kumari, Suchitra, et al.
Publicado: (2021)

Serum lysyl oxidase concentration increases in long-standing systemic sclerosis: Can lysyl oxidase change over time?
por: Jokar, Mohammad Hassan, et al.
Publicado: (2021)

Knock-Out of the Five Lysyl-Oxidase Family Genes Enables Identification of Lysyl-Oxidase Pro-Enzyme Regulated Genes
por: Liburkin-Dan, Tatyana, et al.
Publicado: (2022)

Targeting lysyl oxidase reduces peritoneal fibrosis
por: Harlow, Christopher R., et al.
Publicado: (2017)

Fibrosis in Mesothelioma: Potential Role of Lysyl Oxidases
por: Perryman, Lara, et al.
Publicado: (2022)

Retraction: Lysyl Oxidase Polymorphisms and Susceptibility to Osteosarcoma
Publicado: (2022)

Lysyl oxidase induces epithelial‐mesenchymal transition and predicts intrahepatic metastasis of hepatocellular carcinoma
por: Umezaki, Naoki, et al.
Publicado: (2019)

Inhibition of Lysyl Oxidase and Lysyl Oxidase-Like Enzymes Has Tumour-Promoting and Tumour-Suppressing Roles in Experimental Prostate Cancer
por: Nilsson, Maria, et al.
Publicado: (2016)

Effect of Lysyl Oxidase G473A Polymorphism on Lysyl Oxidase and Total Soluble Collagen Expression in Oral Submucous Fibrosis
por: Mukherjee, Sanjit, et al.
Publicado: (2021)

Lysyl oxidase‐like 2 is a regulator of angiogenesis through modulation of endothelial‐to‐mesenchymal transition
por: de Jong, Olivier G., et al.
Publicado: (2018)

Ultrastructural immunolocalization of lysyl oxidase in vascular connective tissue
Publicado: (1986)

Targeting lysyl oxidase for molecular imaging in breast cancer
por: Wuest, Melinda, et al.
Publicado: (2015)

Lysyl oxidase family members in urological tumorigenesis and fibrosis
por: Li, Tao, et al.
Publicado: (2018)

Role of the lysyl oxidase family in organ development (Review)
por: Wei, Shanzun, et al.
Publicado: (2020)

Lysyl Oxidase (LOX): Functional Contributions to Signaling Pathways
por: Laczko, Rozalia, et al.
Publicado: (2020)

Lysyl oxidases: linking structures and immunity in the tumor microenvironment
por: Tenti, Paolo, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_j6glatdgp4d7ckr74orp3erilp