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Reactive oxygen species contribute to simulated ischemia/reperfusion-induced autophagic cell death in human umbilical vein endothelial cells

BACKGROUND: Autophagy is important for cells to degrade protein aggregates and organelles. Our preliminary study suggests that ischemia/reperfusion in rabbit hearts promoted autophagic myocardial injury, resulting in no-reflow phenomenon. In this study, we sought to further understand the mechanism...

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Detalles Bibliográficos
Autores principales: Zeng, Min, Wei, Xin, Wu, Zhiyong, Li, Wei, Li, Bing, Fei, Yi, He, Yangli, Chen, Jixiong, Wang, Ping, Liu, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074109/
https://www.ncbi.nlm.nih.gov/pubmed/24943908
http://dx.doi.org/10.12659/MSM.890897