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Modeling Glial Contributions to Seizures and Epileptogenesis: Cation-Chloride Cotransporters in Drosophila melanogaster
Flies carrying a kcc loss-of-function mutation are more seizure-susceptible than wild-type flies. The kcc gene is the highly conserved Drosophila melanogaster ortholog of K(+)/Cl(−) cotransporter genes thought to be expressed in all animal cell types. Here, we examined the spatial and temporal requi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074161/ https://www.ncbi.nlm.nih.gov/pubmed/24971529 http://dx.doi.org/10.1371/journal.pone.0101117 |