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Breast cancer cell invasion mediated by Gα12 signaling involves expression of interleukins-6 and −8, and matrix metalloproteinase-2

BACKGROUND: Recent studies on the involvement of the G12 family of heterotrimeric G proteins (Gα12 and Gα13, the products of the GNA12 and GNA13 genes, respectively) in oncogenic pathways have uncovered a link between G12 signaling and cancer progression. However, despite a well characterized role o...

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Detalles Bibliográficos
Autores principales: Chia, Crystal Y, Kumari, Udhaya, Casey, Patrick J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074425/
https://www.ncbi.nlm.nih.gov/pubmed/24976858
http://dx.doi.org/10.1186/1750-2187-9-6