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Stat3 and Gap Junctions in Normal and Lung Cancer Cells

Gap junctions are channels linking the interiors of neighboring cells. A reduction in gap junctional intercellular communication (GJIC) correlates with high cell proliferation, while oncogene products such as Src suppress GJIC, through the Ras/Raf/Erk and other effector pathways. High Src activity w...

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Detalles Bibliográficos
Autores principales: Guy, Stephanie, Geletu, Mulu, Arulanandam, Rozanne, Raptis, Leda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074796/
https://www.ncbi.nlm.nih.gov/pubmed/24670366
http://dx.doi.org/10.3390/cancers6020646