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The Role of STAT3 in Non-Small Cell Lung Cancer

Persistent phosphorylation of signal transducer and activator of transcription 3 (STAT3) has been demonstrated in 22%~65% of non-small cell lung cancers (NSCLC). STAT3 activation is mediated by receptor tyrosine kinases, such as epidermal growth factor receptor (EGFR) and MET, cytokine receptors, su...

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Detalles Bibliográficos
Autores principales: Harada, Daijiro, Takigawa, Nagio, Kiura, Katsuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074799/
https://www.ncbi.nlm.nih.gov/pubmed/24675568
http://dx.doi.org/10.3390/cancers6020708