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BRCA1 and Oxidative Stress

The breast cancer susceptibility gene 1 (BRCA1) has been well established as a tumor suppressor and functions primarily by maintaining genome integrity. Genome stability is compromised when cells are exposed to oxidative stress. Increasing evidence suggests that BRCA1 regulates oxidative stress and...

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Detalles Bibliográficos
Autores principales: Yi, Yong Weon, Kang, Hyo Jin, Bae, Insoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074803/
https://www.ncbi.nlm.nih.gov/pubmed/24704793
http://dx.doi.org/10.3390/cancers6020771