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STAT3 Activity and Function in Cancer: Modulation by STAT5 and miR-146b

The transcription factor STAT3 regulates genes that control critical cellular processes such as proliferation, survival, pluripotency, and motility. Thus, under physiological conditions, the transcriptional function of STAT3 is tightly regulated as one part of a complex signaling matrix. When these...

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Detalles Bibliográficos
Autores principales: Walker, Sarah R., Xiang, Michael, Frank, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074811/
https://www.ncbi.nlm.nih.gov/pubmed/24762632
http://dx.doi.org/10.3390/cancers6020958