Cargando…

Heat Shock Response Associated with Hepatocarcinogenesis in a Murine Model of Hereditary Tyrosinemia Type I

Hereditary Tyrosinemia type 1 (HT1) is a metabolic liver disease caused by genetic defects of fumarylacetoacetate hydrolase (FAH), an enzyme necessary to complete the breakdown of tyrosine. The severe hepatic dysfunction caused by the lack of this enzyme is prevented by the therapeutic use of NTBC (...

Descripción completa

Detalles Bibliográficos
Autores principales: Angileri, Francesca, Morrow, Geneviève, Roy, Vincent, Orejuela, Diana, Tanguay, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074813/
https://www.ncbi.nlm.nih.gov/pubmed/24762634
http://dx.doi.org/10.3390/cancers6020998